Seeking a smooth translation from bench to bedside?
Start with Sodium Hyaluronate from GMP batches.
Lifecore Biomedical has a 40-year history producing products that have impacted more than 150 million patients worldwide. Our sodium hyaluronate (NaHy) is U.S.-manufactured using a microbial fermentation and purification process which sets the industry standard.
Whether you need research-grade, hydrogels, custom modifications, or GMP injectable-grade for clinical or commercial use, we offer a broad range of average molecular weights for your application. Learn more about our Sodium Hyaluronate products, orders, and more by visiting our FAQ page.
Powder is Preferable
Batches are thoroughly mixed prior to rapid, efficient precipitation, yielding pure, uniform NaHy powder that is easy to handle and weigh accurately, providing precise formulation control.
Internal studies of our NaHy powder, using shear rates that are significantly higher than normal for standard formulation processes, demonstrate that molecular weight is well-maintained during high-shear mixing.*
Molecular Weight Maintained in Formulation
*30 min of mixing 0.5% wt HA did not result in substantial molecular weight change(<10% after 30 min of shear). Testing performed with IKA T-25 ULTRA-TURRAX® fitted with S25-18G attachment operated at 20,000 rpm( ≈ 40,000 s-1). ULTRA-TURRAX is a registered trademark of IKA-Werke, Germany.
Benefits of Lifecore Sodium Hyaluronate
- All research products are derived from pharmaceutical GMP batches, ensuring easy translation from pre-clinical programs into clinical trials and commercial manufacturing
- Non-animal-sourced products produced through microbial fermentation
- Stability studies on a variety of commercial products have demonstrated compliance with client’s stability requirements
- Large batch sizes
- Well-designed purification processes
Proven Applications Worldwide
Lifecore CDMO services include the manufacture of >20 commercially approved injectable products containing sodium hyaluronate.
Our sodium hyaluronate has been used as an active device component, excipient, carrier, and API across a wide range of applications, including:
- Ophthalmology
- Orthopedics
- Drug delivery
- Biomaterials
- Aesthetics
- Oncology
- Pain management
Standard Products for Research Use
All Research-Use NaHy is
derived from GMP batches with an average molecular weight from
5 KDa-1.8 MDa.
Hydrogels for Drug Delivery
Corgel® BioHydrogel products are biocompatible and can be tailored for use across various medical applications.
GMP & Custom Modifications
Corgel® BioHydrogel technology is covered by US patents 6,982,298; 7,368,502; 7,465,766. Cleveland Clinic is a © of The Cleveland Clinic Foundation. Lifecore Biomedical and Corgel are trademarks of Lifecore Biomedical.